Postnatal changes in insulin binding in slow and fast-twitch rabbit skeletal muscles

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Postnatal changes in insulin binding in slow and fast-twitch rabbit skeletal muscles.

Changes of insulin binding characteristics (number of receptors, Kd) were studied in the semimembranosus proprius (SMP) and psoas major (PM) muscle from birth to adult stage. The Kd was about 0.15 10(-9) M in both muscles and did not change with age. The numbers of receptors were similar in both muscles at birth and changed differently thereafter to reach 1.3 fmoles per mg of muscle in the PM a...

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Introduction: Skeletal muscle is a flexible and ever changing tissue and the role of costameric proteins in its response to different stimuli is not well defined. The aim of this study was to investigate the effect of progressive resistance exercise on β1 integrin and vinculin proteins in fast and slow twitch skeletal muscles of male rats. Methods: Twelve male Wistar rats (weight: 298±5.2 gr...

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Background and Aims: Klotho protein is a substance effective in increasing life expectancy. Moreover, it prevents muscle atrophy, osteoporosis, and cardiovascular disease. Therefore, the present aimed to assess changes in the expression of klotho protein and insulin-like growth factor 1 (IGF-1) genes in the muscles of aged Wistar rats after eight weeks of resistance training. Materials and Met...

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ژورنال

عنوان ژورنال: Reproduction Nutrition Développement

سال: 1988

ISSN: 0181-1916

DOI: 10.1051/rnd:19880518